Research Article

Anti-Inflammatory, Immunomodulatory, and Antioxidant Activities of Allicin, Norfloxacin, or Their Combination against Pasteurella multocida Infection in Male New Zealand Rabbits

Table 1

The effect of allicin, norfloxacin, and their combination treatment in Pasteurella multocida type B infection in male white New Zealand rabbits on hematological parameters.

ParametersGroups
ControlInfectedInfection + allicinInfection + NfInfection + Nf + allicin

RBCs (106/mm3)4.51 ± 0.04a3.63 ± 0.09bc3.51 ± 0.03bc3.43 ± 0.04c3.58 ± 0.06bc
Hb (g/dl)8.68 ± 0.05a6.56 ± 0.7c6.64 ± 0.12c6.44 ± 0.07c6.96 ± 0.08b
PCV%36.40 ± 0.65a31.98 ± 0.52b31.56 ± 0.66b30.78 ± 0.19b31.20 ± 0.31b
MCV/FL80.58 ± 0.76b90.02 ± 1.18a89.85 ± 2.21a89.55 ± 0.79a87.14 ± 1.65a
MCHC%23.85 ± 0.36a20.49 ± 024c21.05 ± 0.26c21.04 ± 0.19c22.26 ± 0.17b
WBCs (103/mm3)6.35 ± 0.06d7.35 ± 0.12b7.15 ± 0.07bc8.01 ± 0.26a6.84 ± 0.06c
Neutrophil (103/mm3)1.31 ± 0.01d3.41 ± 0.08b3.00 ± 0.08c3.82 ± 0.14a2.87 ± 0.03c
Eosinophil (103/mm3)0.13 ± 00c0.18 ± 0.03bc0.17 ± 0.04bc0.31 ± 0.02a0.22 ± 0.04b
Lymphocyte (103/mm3)4.83 ± 0.06a3.25 ± 0.13bc3.53 ± 0.12b3.42 ± 0.08bc3.18 ± 0.03c
Monocyte (103/mm3)0.13 ± 00b0.15 ± 0.07a0.41 ± 0.03a0.44 ± 0.07a0.44 ± 0.03a
Phagocytic%41.8 ± 0.49 e53.00 ± 0.32 d58.2 ± 0.200 c64.60 ± 0.400 b76.4 ± 0.51 a
Phagocytic index0.34 ± 0.01e0.53 ± 0.01 d0.59 ± 0.003 c0.65 ± 0.013 b0.84 ± 0.005 a

Values are represented as (). Means within the same row carrying different superscripts (a, b, c, and d) are significant at . Hb: hemoglobin; MCHC: mean corpuscle hemoglobin concentration; MCV: mean corpuscle volume; Nf: norfloxacin; PCV: packed cell volume; RBCs: red blood cells; WBCs: white blood cells.