Anti-Inflammatory, Immunomodulatory, and Antioxidant Activities of Allicin, Norfloxacin, or Their Combination against Pasteurella multocida Infection in Male New Zealand Rabbits
Table 1
The effect of allicin, norfloxacin, and their combination treatment in Pasteurella multocida type B infection in male white New Zealand rabbits on hematological parameters.
Parameters
Groups
Control
Infected
Infection + allicin
Infection + Nf
Infection + Nf + allicin
RBCs (106/mm3)
4.51 ± 0.04a
3.63 ± 0.09bc
3.51 ± 0.03bc
3.43 ± 0.04c
3.58 ± 0.06bc
Hb (g/dl)
8.68 ± 0.05a
6.56 ± 0.7c
6.64 ± 0.12c
6.44 ± 0.07c
6.96 ± 0.08b
PCV%
36.40 ± 0.65a
31.98 ± 0.52b
31.56 ± 0.66b
30.78 ± 0.19b
31.20 ± 0.31b
MCV/FL
80.58 ± 0.76b
90.02 ± 1.18a
89.85 ± 2.21a
89.55 ± 0.79a
87.14 ± 1.65a
MCHC%
23.85 ± 0.36a
20.49 ± 024c
21.05 ± 0.26c
21.04 ± 0.19c
22.26 ± 0.17b
WBCs (103/mm3)
6.35 ± 0.06d
7.35 ± 0.12b
7.15 ± 0.07bc
8.01 ± 0.26a
6.84 ± 0.06c
Neutrophil (103/mm3)
1.31 ± 0.01d
3.41 ± 0.08b
3.00 ± 0.08c
3.82 ± 0.14a
2.87 ± 0.03c
Eosinophil (103/mm3)
0.13 ± 00c
0.18 ± 0.03bc
0.17 ± 0.04bc
0.31 ± 0.02a
0.22 ± 0.04b
Lymphocyte (103/mm3)
4.83 ± 0.06a
3.25 ± 0.13bc
3.53 ± 0.12b
3.42 ± 0.08bc
3.18 ± 0.03c
Monocyte (103/mm3)
0.13 ± 00b
0.15 ± 0.07a
0.41 ± 0.03a
0.44 ± 0.07a
0.44 ± 0.03a
Phagocytic%
41.8 ± 0.49 e
53.00 ± 0.32 d
58.2 ± 0.200 c
64.60 ± 0.400 b
76.4 ± 0.51 a
Phagocytic index
0.34 ± 0.01e
0.53 ± 0.01 d
0.59 ± 0.003 c
0.65 ± 0.013 b
0.84 ± 0.005 a
Values are represented as (). Means within the same row carrying different superscripts (a, b, c, and d) are significant at . Hb: hemoglobin; MCHC: mean corpuscle hemoglobin concentration; MCV: mean corpuscle volume; Nf: norfloxacin; PCV: packed cell volume; RBCs: red blood cells; WBCs: white blood cells.