Anti-Inflammatory, Immunomodulatory, and Antioxidant Activities of Allicin, Norfloxacin, or Their Combination against Pasteurella multocida Infection in Male New Zealand Rabbits
Table 3
The effect of allicin, norfloxacin, and their combination treatment in Pasteurella multocida type B infection in male white New Zealand rabbits on some hepatic markers.
Parameters
Groups
Control
Infected
Infection + allicin
Infection + NF
Infection + NF + allicin
ALT (U/L)
34.2 ± 1.06d
48.20 ± 0.20a
37.4 ± 0.87c
44.00 ± 0.44b
37.20 ± 1.07c
ALP (U/L)
66.25 ± 1.04c
124.41 ± 1.09a
83.74 ± 1.81b
68.19 ± 0.76c
68.22 ± 0.73c
LDH (U/L)
617.70 ± 4.03d
1105.63 ± 2.25a
800.56 ± 24.22b
683.74 ± 4.84c
646.44 ± 1.61d
Total bilirubin (mg/dl)
1.27 ± 0.004d
3.04 ± 0.004a
1.93 ± 0.024b
1.58 ± 0.124c
1.40 ± 0.044d
Direct bilirubin (mg/dl)
0.36 ± 0.014d
1.14 ± 0.029a
0.81 ± 0.013b
0.54 ± 0.040c
0.31 ± 0.002d
Indirect bilirubin (mg/dl)
0.91 ± 0.015c
1.90 ± 0.032a
1.12 ± 0.025b
1.04 ± 0.115bc
1.09 ± 0.043bc
Values are represented as (). Means within the same row carrying different superscripts (a, b, c, and d) are significant at . ALP: alkaline phosphatase; ALT: alanine transferase; LDH: lactate dehydrogenase; NF: norfloxacin.