Oxidative Medicine and Cellular Longevity / 2018 / Article / Tab 2

Review Article

Anticancer Properties of Graviola (Annona muricata): A Comprehensive Mechanistic Review

Table 2

AGEs of A. muricata reported to have anticancer activities. Structures were drawn using ChemDraw, Arial, point 20.

Compound namesStructureMolecular formulaMWT (g/mol)Cancer cell lines tested on

Annocatacin AC35H62O6578.88Hepatic (Hep G2 and Hep 2,2,15) cancer [80]
Annocatacin BC35H62O6578.88Hepatic (Hep G2 and Hep 2,2,15) cancer [80]
AnnocatalinC35H64O7596.89Hepatic (Hep G2 and Hep 2,2,15) cancer [81]
AnnohexocinC35H64O9628.888Breast (MCF-7), prostate (PC-3), colorectal (HT-29), lung (A549), renal (A498) and pancreatic (PACA-2) cancers [34]
Annomuricin AC35H64O8612.889Breast (MCF-7), colorectal (HT-29), lung (A549) [17], and leukemic (U-937) [46] cancers
Annomuricin BC35H64O8612.889Breast (MCF-7), colorectal (HT-29), and lung (A549) cancers [17]
Annomuricin CC35H64O8612.889Breast (MCF-7), colorectal (HT-29), and lung (A549) cancers [86]
Annomuricin EC35H64O8612.889Breast (MCF-7), prostate (PC-3), lung (A549), renal (A498), pancreatic (PACA) [16], and colorectal (HT-29) cancers [16, 25]
AnnomutacinC37H68O7624.944Breast cancer (MCF-7), colorectal (HT-29), and lung cancers (A549) [43]
AnnonacinC35H64O7596.89
Annonacin AC35H64O7596.89Leukemia (U-937) [46]
AnnonacinoneC35H62O7594.874Oral cancer (KB) [35]
Annopentocin AC35H64O8612.889Breast (MCF-7), prostate (PC-3), colorectal (HT-29), lung (A549), renal (A498), and pancreatic (PACA-2) cancers [32]
Annopentocin BC35H64O8612.889Breast (MCF-7), prostate (PC-3), colorectal (HT-29), lung (A549), renal (A498), and pancreatic (PACA-2) cancers [32]
Annopentocin CC35H64O8612.889Breast (MCF-7), prostate (PC-3), colorectal (HT-29), lung (A549), renal (A498), and pancreatic (PACA-2) cancers [32]
ArianacinC35H64O7596.89Breast (MCF-7), colorectal (HT-29), and lung (A549) cancers [85]
CorossolinC35H64O6580.891Hepatic (Hep G2 and Hep 2,2,15) [82] and oral (KB) cancers [35]
CorossoloneC35H62O6578.875Hepatic cancer (Hep G2 and Hep 2,2,15) [82] and oral (KB) cancers [35, 83]
GigantetrocinC35H64O7596.89Breast (MCF-7), colorectal (HT-29), and lung (A549) cancers [49]
Gigantetrocin AC35H64O7596.89Breast (MCF-7), colorectal (HT-29), and lung (A549) cancers [50]
Gigantetrocin BC35H64O7596.89Breast (MCF-7), colorectal (HT-29), and lung (A549) cancers [17, 50]
GoniothalamicinC35H64O7596.89Breast (MCF-7), colorectal (HT-29), and lung (A549) cancers [49]
IsoannonacinC35H64O7596.89Breast (MCF-7), colorectal (HT-29), and lung (A549) cancers [48]
Isoannonacin-10-oneC35H62O7594.874Breast (MCF-7), colorectal (HT-29), and lung (A549) cancers [49]
JavoricinC35H64O7596.89Breast (MCF-7), colorectal (HT-29), and lung (A549) cancers [85]
LongifolicinC35H64O6580.891Hepatic (Hep G2 and Hep 2,2,15) cancer [82]
MuricapentocinC35H64O8612.889Breast (MCF-7), prostate (PC-3), colorectal (HT-29), lung cancer (A549), renal (A498), and pancreatic (PACA) cancers [16]
MuricatacinC17H32O3284.44Breast (MCF-7), colorectal (HT-29), and lung (A549) cancers [48]
Muricatetrocin AC35H64O7596.89Breast (MCF-7), colorectal (HT-29), and lung (A549) cancers [17, 50]
Muricatetrocin BC35H64O7596.89Breast (MCF-7), colorectal (HT-29), and lung (A549) cancers [17, 50]
Muricatocin AC35H64O8612.889Breast (MCF-7), colorectal (HT-29) and lung (A549) cancers [44]
Muricatocin BC35H64O8612.889Breast (MCF-7), colorectal (HT-29), and lung (A549) cancers [44]
Muricatocin CC35H64O8612.889Breast (MCF-7), colorectal (HT-29), and lung (A549) cancers [86]
MuriceninProstate (PC-3) cancer [30]
Muricin AC35H64O7596.878Hepatic (Hep G2 and Hep 2,2,15) cancer [82]
Muricin BC35H64O7596.878Hepatic (Hep G2 and Hep 2,2,15) cancer [82]
Muricin CC35H64O7596.878Hepatic (Hep G2 and Hep 2,2,15) cancer [82]
Muricin DC33H60O7568.836Hepatic (Hep G2 and Hep 2,2,15) cancer [82]
Muricin EHepatic (Hep G2 and Hep 2,2,15) cancer [82]
Muricin FC35H62O7594.874Hepatic (Hep G2 and Hep 2,2,15) cancer [82]
Muricin GHepatic (Hep G2 and Hep 2,2,15) cancer [82]
Muricin HC35H64O6580.891Hepatic (Hep G2 and Hep 2,2,15) cancer [81]
Muricin IC37H66O6606.929Hepatic (Hep G2 and Hep 2,2,15) cancer [81]
Muricin JC22H38O7414.2618Prostate (PC-3) cancer [29]
Muricin KC24H42O7442.2931Prostate (PC-3) cancer [29]
Muricin LC24H42O7442.2931Prostate (PC-3) cancer [29]
Muricin MC24H42O7442.2931Prostate (PC-3) cancer [30]
Muricin NC22H38O7414.2618Prostate (PC-3) cancer [30]
MuricoreacinC35H64O9628.4550Breast (MCF-7), prostate (PC-3), colorectal (HT-29), lung cancer (A549), renal cancer (A498), and pancreatic (PACA-2) cancers [47]
Murihexocin AC35H64O9628.888Breast (MCF-7), prostate (PC-3), colorectal (HT-29), lung (A549), renal (A498), and pancreatic (PACA-2) cancers [15]
Murihexocin BC35H64O9628.4550Breast (MCF-7), prostate (PC-3), colorectal (HT-29), lung (A549), renal (A498), and pancreatic (PACA-2) cancers [15]
Murihexocin CC31H56O9572.3924Breast (MCF-7), prostate (PC-3), colorectal (HT-29), lung cancer (A549), renal cancer (A498), and pancreatic (PACA-2) cancers [47]
MurisolinC35H63NO6593.4655Oral (KB) cancer [35]
SolaminC35H64O5564.892Oral (KB) cancer [35]
VinblastineC46H58N4O9810.989Oral (KB) cancer [35]
cis-AnnomontacinC37H68O7624.4965Hepatic (Hep G2 and Hep 2,2,15) cancer [88]
cis-AnnonacinC35H64O7596.88Breast (MCF-7), colorectal (HT-29), and lung (A549) cancers [85]
cis-Annonacin-10-oneC35H62O7594.874Breast (MCF-7), colorectal (HT-29), and lung (A549) cancers [85]
cis-CorossoloneC35H62O6578.875Hepatic (Hep G2 and Hep 2,2,15) cancer [81]
cis-GoniothalamicinC35H64O7596.89Breast (MCF-7), colorectal (HT-29), and lung (A549) cancers [85]

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