Review Article

Methane Medicine: A Rising Star Gas with Powerful Anti-Inflammation, Antioxidant, and Antiapoptosis Properties

Table 2

The indicators that are used to identify the properties of methane.

PathologyMakersTrend

AntioxidaseSOD
CAT
GSH
Increase

Oxidative stressMDA
4-HNE
8-OHdG
MPO
3-NT
DAO
Decline

Inflammation factorIL-1β
IL-6
ICAM-1
IL-12
TNF-α
IFN-γ
CCL2
CXCL1
Decline

Inflammation signalMAPK
Lyn-P
JNK
ERK
NF-κB
Decline

ApoptosisTUNEL
Caspase-3
Caspase-9
Caspase-12
Bcl-2
Decline
Nuclear factorNrf2Activation