Isobavachalcone Induces ROS-Mediated Apoptosis <i>via</i> Targeting Thioredoxin Reductase 1 in Human Prostate Cancer PC-3 Cells

<div>Effect of IBC treatment on PC-3 cell morphology and apoptosis. Cells were exposed to 15, 30, or 45 <i>μ</i>M IBC for 24 h. (a) After treating cells for 24 h, the morphology of PC-3 cells was visualized and imaged by inverted phase contrast microscopy. (b) The morphological changes in PC-3 cells were examined following staining with Hoechst dye 33258. (c) Rate of apoptotic cells of IBC-treated PC-3 cells as detected by flow cytometry. (d) Quantitative analysis of the rate of apoptotic cells after IBC treatment. 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Oxidative Medicine and Cellular Longevity

fig2

Figure 2

Figure 2: Isobavachalcone Induces ROS-Mediated Apoptosis <i>via</i> Targeting Thioredoxin Reductase 1 in Human Prostate Cancer PC-3 Cells 

Oxidative Medicine and Cellular Longevity

Isobavachalcone Induces ROS-Mediated Apoptosis via Targeting Thioredoxin Reductase 1 in Human Prostate Cancer PC-3 Cells

Figure 2