The Good, the Bad, and the Ugly of ROS: New Insights on Aging and Aging-Related Diseases from Eukaryotic and Prokaryotic Model Organisms

Figure 5

(a) All cell divisions in rod-shaped bacteria are asymmetric in that one daughter cell inherits the “new” pole (green) from a previous division and the other inherits the “old” pole (red). In some bacteria, this asymmetry is used to create functional specialization of daughter cells. (b) In C. crescentus, different polar appendages form at the new and old poles, leading to dimorphic daughter cells. (c) In Mycobacterium, cells preferentially grow at the old pole (marked with an arrow). Daughter cells that inherit the old pole, called accelerators, continue growing whereas those inheriting the new pole, called alternators, must form a new growth pole before elongating. Reproduced with permission from Aakre CD, Laub MT. Asymmetric cell division: a persistent issue? Developmental cell. 2012; 22 (2):235-236. doi:10.1016/j.devcel.2012.01.016.

(a)

(b)

(c)