Anti-Inflammatory and Antioxidant Actions of Methyl Jasmonate Are Associated with Metabolic Modifications in the Liver of Arthritic Rats

Table 2

Plasma parameters of inflammation and liver/renal damage. C, controls treated with corn oil; C300, controls treated with MeJA at the dose of 300 mg·kg⁻¹; A: arthritic rats treated with corn oil; A300: arthritic rats treated with MeJA at the dose of 300 mg·kg⁻¹; IBU: arthritic rats treated with ibuprofen at the dose of 30 mg·kg⁻¹.

Parameter	Groups
	C	C300	A	A300	IBU
AST (U·L^−1)	37.6 ± 1.6^a	36.6 ± 3.9^a	77.4 ± 2.8^b	52.4 ± 1.6^a	60.6 ± 3.6^c
ALT (U·L^−1)	18.9 ± 0.8^a	18.6 ± 0.6^a	16.5 ± 1.1^a	19.0 ± 0.6^a	26.1 ± 0.6^a
ALP (U·L^−1)	60.7 ± 7.7^a	59.0 ± 5.4^a	139 ± 11^b	81.1 ± 8.1^a	151 ± 5.9^b
Total protein (g·dL^−1)	5.9 ± 0.3^a	5.8 ± 0.3^a	5.9 ± 0.1^a	5.6 ± 0.1^a	5.8 ± 0.2^a
Albumin (g·dL^−1)	2.3 ± 0.2^a	2.3 ± 0.1^a	1.3 ± 0.1^b	1.6 ± 0.1^b	2.1 ± 0.1^a
Globulin (g·dL^−1)	3.5 ± 0.5^a	3.4 ± 0.1^a	4.6 ± 0.1^b	3.9 ± 0.2^a	3.7 ± 0.2^a
Albumin/globulin (A/G ratio)	0.7 ± 0.1^a	0.7 ± 0.1^a	0.3 ± 0.01^b	0.4 ± 0.04^b	0.6 ± 0.02^a
Creatinine (mg·dL^−1)	0.4 ± 0.1^a	0.4 ± 0.1^a	0.6 ± 0.01^a	0.6 ± 0.02^a	0.8 ± 0.1^b
MPO activity (nmol·min^−1·mg^−1)	2.3 ± 0.3^a	3.1 ± 0.2^a	14.7 ± 1.4^b	8.4 ± 1.1^c	8.3 ± 0.8^c

The data are the error of the mean of 5 animals. Values with different superscript letters in the same line are different.