Hypothyroidism Causes Endoplasmic Reticulum Stress in Adult Rat Hippocampus: A Mechanism Associated with Hippocampal Damage

Table 1

Redox environment alterations in the hippocampus of thyroidectomized rats at different periods of time.

	3rd week		4th week
	Euthyroid	Hypothyroid	Euthyroid	Hypothyroid
GSH (μg GSH/mg protein)	426.66 ± 36.16	452.02 ± 41.76	447.59 ± 32.35	332.94 ± 36.16^,
GSSG (μg GSSG/mg protein)	1.33 ± 0.25	1.51 ± 0.22	1.40 ± 0.19	1.42 ± 0.19
Index GSH^2/GSSG	145318.53 ± 27632.49	130329.80 ± 27632.49	155529.19 ± 23930.43	76109.75 ± 27632.49^,
γ-Glutamyl transpeptidase activity (UgGT/min/mg protein)	1.27 ± 0.37	3.04 ± 0.59	1.27 ± 0.37	5.34 ± 0.59^,

Values are expressed as the mean ± SEM. versus the euthyroid group; versus the third week hypothyroid group ().