Anacardium microcarpum Promotes Neuroprotection Dependently of AKT and ERK Phosphorylation but Does Not Prevent Mitochondrial Damage by 6-OHDA

Table 2

Activity of antioxidant enzymes in cortical slices submitted to treatment with the neurotoxin 6-OHDA and A. microcarpum methanolic fraction.

	GST; (mg/mU protein)	GPx; (mg/mU protein)	TrxR; (mg/mU protein)
Control	241.2 ± 8.49	41.37 ± 5.01	2.375 ± 0.342
6-OHDA 500 μM	406.4 ± 75.89	23.82 ± 2.07	4.675 ± 0.608
AMMF 100 μg/mL	186.2 ± 42.13^#	51.01 ± 4.04	2.459 ± 0.137^##
AMMF 100 μg/mL + 6-OHDA 500 μM	251.5 ± 36.48^#	46.29 ± 3.20^##	3.164 ± 0.496^#

Data are expressed as percentage of the untreated control ± SEM. in relation to control group, # in relation to control group, ## in relation to 6-OHDA group.