Anacardium microcarpum Promotes Neuroprotection Dependently of AKT and ERK Phosphorylation but Does Not Prevent Mitochondrial Damage by 6-OHDA

Table 3

Effect of treatment with 6-OHDA and A. microcarpum on GSH and GSSG levels and ratio GSH/GSSG.

	GSH; (% of control)	GSSG; (% of control)	Total glutathione; (% of control)	GSH/GSSG; (% of control)
Control	88.05 ± 6.73	90.60 ± 5.48	100.0 ± 10.66	100.0 ± 2.51
6-OHDA 500 μM	87.49 ± 5.41	61.61 ± 12.87	66.56 ± 11.34	168.1 ± 19.64
AMMF 100 μg/mL	136.7 ± 6.54	117.2 ± 10.04^##	129.7 ± 4.18^##	120.7 ± 9.21^##
AMMF 100 μg/mL + 6-OHDA 500 μM	111.4 ± 13.28	111.9 ± 3.17^##	111.8 ± 4.96^#	99.61 ± 8.99^##

Data are expressed as percentage of the untreated control ± SEM. ; in relation to control group. ## when compared to 6-OHDA group.