Changes of Plasma FABP4, CRP, Leptin, and Chemerin Levels in relation to Different Dietary Patterns and Duodenal-Jejunal Omega Switch Surgery in Sprague–Dawley Rats

Table 1

FABP4, CRP, leptin, and chemerin plasma levels 8 weeks after DJOS (1st column) and SHAM (2nd column) surgery, subjected to 16 weeks of different dietary patterns and intergroup comparison between DJOS and SHAM study groups (3rd column) using descriptive statistics and results of two-way analysis of variance.

Parameter	DJOS				SHAM				ANOVA
	HF/HF	HF/CD	CD/HF	CD/CD	HF/HF	HF/CD	CD/HF	CD/CD	Group	Op.	Int.
FABP4 (ng/ml)	393.0 ± 46.3	391.8 ± 51.6	397.7 ± 42.1	210.4 ± 66.3	407.1 ± 50.0	428.7 ± 48.1	348.0 ± 31.0	293.4 ± 46.5	<0.001	0.133	<0.05
CRP (ng/ml)	17.3 (12.2–19.5)	19.4 (18.9–0.4)	11.6 (5.6–14.3)	1.5 (1.1–6.6)	31.9 (31.7–32.2)	27.3 (12.3–28.6)	60.2 (58.8–61.0)	11.0 (2.0–15.6)		<0.001
Leptin (ng/ml)	12.8 ± 3.4	10.4 ± 2.7	10.8 ± 2.6	3.8 ± 0.6	18.3 ± 1.2	17.0 ± 1.6	16.3 ± 2.4	8.3 ± 2.4	<0.001	<0.001	0.697
Chemerin (ng/ml)	20.6 ± 6.8	15.5 ± 4.1	16.9 ± 4.2	7.8 ± 1.4	35.8 ± 6.7	23.3 ± 2.3	20.1 ± 4.3	15.2 ± 3.5	<0.001	<0.001	<0.05

Statistical significance was set at a . FABP4: fatty acid-binding protein 4; CRP: C-reactive protein; DJOS: duodenal-jejunal omega switch surgery; HF: high-fat diet; CD: control diet; HF/HF, CD/HF, HF/CD, CD/CD: type of diet 8 weeks before/8 weeks after surgery; Op.: operation type; Int.: interaction between group and operation type; mean ± standard deviation or median (lower–upper quartile).