Methyl Chavicol and Its Synthetic Analogue as Possible Antioxidant and Antilipase Agents Based on the In Vitro and In Silico Assays
Table 3
Concentration of malonaldehyde (MDA) obtained by the thiobarbituric acid method.
Sample
Concentration (mg)
MDA content (μM)
Day 0
Day 1
Day 2
Day 3
Day 4
Control
Saline
0.42 ± 0.02
0.59 ± 0.04
0.67 ± 0.06
0.64 ± 0.03
0.91 ± 0.08
BHT
7.5
0.08 ± 0.02
0.16 ± 0.02
0.12 ± 0.03
0.16 ± 0.00
0.22 ± 0.05
15
0.10 ± 0.02
0.11 ± 0.03
0.08 ± 0.01
0.17 ± 0.06
0.16 ± 0.01
30
0.20 ± 0.01
0.20 ± 0.03
0.23 ± 0.06
0.12 ± 0.08
0.22 ± 0.08
MC
7.5
0.41 ± 0.01
0.18 ± 0.02
0.22 ± 0.06
0.22 ± 0.06
0.16 ± 0.02
15
0.39 ± 0.06
0.29 ± 0.04
0.53 ± 0.06
0.32 ± 0.07
0.21 ± 0.08
30
0.35 ± 0.02
0.20 ± 0.01
0.40 ± 0.06
0.38 ± 0.03
0.22 ± 0.02
MPMO
7.5
0.24 ± 0.02
0.39 ± 0.07
0.46 ± 0.01
0.35 ± 0.03
0.54 ± 0.04
15
0.20 ± 0.01
0.25 ± 0.00
0.37 ± 0.05
0.39 ± 0.01
0.38 ± 0.01
30
0.18 ± 0.06
0.26 ± 0.02
0.32 ± 0.00
0.37 ± 0.01
0.34 ± 0.05
The values correspond to the mean ± SEM (). BHT: 3,5-di-tert-butyl-4-hydroxy toluene; MC: methyl chavicol; MPMO: 2-[(4-methoxyphenyl)methyl]oxirane. The means differed from those of the negative control (saline) after analysis of variance followed by Tukey’s HSD (honest significant difference) test for .
