Resveratrol Can Be Stable in a Medium Containing Fetal Bovine Serum with Pyruvate but Shortens the Lifespan of Human Fibroblastic Hs68 Cells

Table 2

Effect of catalase or pyruvate on Res degradation in DMEM.

	Catalase	Pyruvate
Day 0	100 ± 2.5	100 ± 4.7
Day 1	84.8 ± 3.7	56.4 ± 2.9
Day 7	28.6 ± 3.4	10.4 ± 3.1

Res at 200 μM was incubated for 0–7 days in DMEM, which contained 3.7 g/L sodium bicarbonate with 100 U/mL catalase or pyruvate (1 mM) at 37°C in a CO₂ incubator supplied with 5% CO₂. The remaining Res (%) levels related to the peak area of Res on day 0 were determined by HPLC. Values (mean ± standard deviation; ) in the same column without a common letter are significantly different ().