Indoleamine 2,3-Dioxygenase-Dependent Neurotoxic Kynurenine Metabolism Contributes to Poststroke Depression Induced in Mice by Ischemic Stroke along with Spatial Restraint Stress

Figure 10

Schematic illustration of the potential mechanism by which IDO1 and IDO1-dependent kynurenine metabolite, QUIN, are involved in PSD animal models and the therapeutic effects of antidepressant aripiprazole.