Research Article

Indoleamine 2,3-Dioxygenase-Dependent Neurotoxic Kynurenine Metabolism Contributes to Poststroke Depression Induced in Mice by Ischemic Stroke along with Spatial Restraint Stress

Table 1

IDO1 immunoreactivity in the brain of PSD group mice.

IDO/marker+ cells (%)IDO+/marker+ cells (%)
IDO/NeuN+IDO/GFAP+IDO/Iba-1+IDO+/NeuN+IDO+/GFAP+IDO+/Iba-1+

NAc68.15 ± 5.0974.39 ± 4.0836.16 ± 5.4331.85 ± 5.0925.61 ± 4.0863.84 ± 5.43
Hippo77.87 ± 5.2061.77 ± 3.5235.10 ± 4.0622.13 ± 5.2038.23 ± 3.5264.90 ± 4.06
Hypo67.20 ± 2.8754.55 ± 3.2133.79 ± 2.4532.80 ± 2.8745.45 ± 3.2166.21 ± 2.45