Research Article
Mitofusin2 Induces Cell Autophagy of Pancreatic Cancer through Inhibiting the PI3K/Akt/mTOR Signaling Pathway
Figure 5
Mfn2 promotes cell autophagy by inhibiting the PI3K/AKT/mTOR signaling pathway. (a) Quantification of Western blots for p-PI3K expressions in the Ad-Mfn2 group compared to the control group and Ad-Mfn2+ IGF-1 group (; ). (b) Quantification of Western blots for p-AKT expressions in the Ad-Mfn2 group compared to the control group and Ad-Mfn2+ IGF-1 group (; ). (c) Quantification of Western blots for p-mTOR expressions in the Ad-Mfn2 group compared to the control group and Ad-Mfn2+ IGF-1 group (; ). (d) Western blotting was used to detect the expression of p-PI3K, p-Akt, and p-mTOR in pancreatic cancer cells.
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