Guazuma ulmifolia Lam. Decreases Oxidative Stress in Blood Cells and Prevents Doxorubicin-Induced Cardiotoxicity

Table 1

Identification of the constituents from extracts of G. ulmifolia by LC-DAD-MS/MS.

Peak	RT (min)	Compound	UV (nm)	FM	Negative mode (m/z)		Positive mode (m/z)
					MS [M−H]^-	MS/MS	MS [M+H]^+
					341.1090	—	—
2	1.2	NI	—	C6H10O8	209.0303	—	—
3	1.2	Quinic acid	—	C7H12O6	191.0571	—	193.0717
4	1.4	Citric acid	—	C6H8O7	191.0198	—	193.0343
5	1.5	Citric acid derivative	—	C6H8O7	191.0195	—	193.0341
6	2.4	NI	—	C14H18O9	329.0882	—	—
7	4.4	NI	—	C14H19NO7	312.1078	—	336.1057^Na
8	5.8	NI	—	C11H12N2O2	203.0814		205.0970
9	8.6	Epigallocatechin	278	C15H14O7	305.0687	—	—
10	9.1	Catechin	278	C15H14O6	289.0735	—	—
11	9.2	PCY-PCY	278	C30H26O12	577.1345	289	579.1501
12	9.5	PDE-PCY	280	C30H26O13	593.1324		—
13	10.2	NI	280	C15H18O8	325.0928		—
14	10.7	5-O-E-Caffeoylquinic acid	299,325	C16H18O9	353.0894	191	355.1030
15	11.9	NI	—	C15H19NO8	340.1046	—	—
16	12.1	PCY-PCY	280	C30H26O12	577.1357	407,3399,289,245,161	579.1497
17	12.5	Epicatechin	280	C15H14O6	289.0716	245,221,187,165	291.0880
18	14.6	PCY-PFI	280	C30H26O11	561.1393	289,245,205,179,164	563.1580
19	15.6	NI	280	C13H14N2O3	245.0940	—	—
20	16.8	Di-O-deoxyhexosyl-hexosyl quercetin	270,355	C33H40O20	755.2035	300,271,255,179	757.2218
21	17.1	Di-O-deoxyhexosyl-hexosyl quercetin	270,355	C33H40O20	755.2044	300,271,255,179	757.2193
22	17.8	O-Deoxyhexosyl-hexosyl quercetin	265,350	C27H30O16	609.1472	300,271,255,243	611.1628
23	18.1	O-Deoxyhexosyl-hexosyl quercetin	265,350	C27H30O16	609.1467	300,271,255	611.1640
24	18.5	O-Hexosyl quercetin	270,350	C21H20O12	463.0903	300,271,255,243	465.1036
25	18.6	O-Deoxyhexosyl-hexosyl quercetin	265,355	C27H30O16	609.1473	300,271,255,179	611.1624
		Di-O-deoxyhexosyl-hexosyl kaempferol		C33H40O19	739.2087	284	741.2210
26	18.6	PCY-PCY	280	C30H26O12	577.1375	289	579.1508
27	18.9	O-Hexosyl quercetin	265,355	C21H20O12	463.0893	300	465.1072
28	20.0	O-Pentosyl quercetin	265,350	C20H18O11	433.0775	300,271,255,243	435.0918
29	20.2	O-Deoxyhexosyl quercetin	265,350	C21H20O11	447.0937	300	449.1091
30	20.6	O-Deoxyhexosyl hexosyl luteolin	265,337	C27H30O15	593.1498	284,255,227	595.16699

Confirmed by authentic standard. NI: nonidentified; PDE: prodelphinidin; PFI: profisetinidin; PCY: procyanidin; RT: retention time; —: non-observed/detected means.