Oxidative Medicine and Cellular Longevity / 2018 / Article / Fig 4

Review Article

SIRT3 a Major Player in Attenuation of Hepatic Ischemia-Reperfusion Injury by Reducing ROS via Its Downstream Mediators: SOD2, CYP-D, and HIF-1α

Figure 4

Illustration of surgical and pharmacological Ischemic preconditioning (IPC) via multiple pathways that modulates inflammation and reduces oxidative stress by decreasing mitochondrial ROS. Please find detail explanation in Ischemic Preconditioning (IPC). Adenosine A1 receptors (A1R), deferoxamine (DFX), heme oxygenase-1 (HO-1), intermittent clamping (IC), and induced nitric oxide synthetase (iNOS).

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