Immunomodulatory Effects of Diterpene Quinone Derivatives from the Roots of Horminum pyrenaicum in Human PBMC

Figure 1

Concentrations of neopterin (Neo), tryptophan (Trp), kynurenine (Kyn) as well as the Kyn/Trp, a measure of IDO-1 activity, in the supernatant of unstimulated PBMC and cells stimulated with 10 μg/mL concanavalin A (Con A) or phytohaemagglutinin (PHA) for 48 h. Results shown are the mean values ± SEM of seven independent experiments run in duplicates (, compared to unstimulated cells; please note log-scale).