Research Article
Coenzyme Q10 Prevents Senescence and Dysfunction Caused by Oxidative Stress in Vascular Endothelial Cells
Figure 7
Preincubation with CoQ10H2 prevented H2O2 or HG-induced reduction in migration and tube formation by HUVECs. (a) Representative images of cell migration analysis evaluated using a wound-healing assay conducted over 12 hours in H2O2-induced reduction of migration. (b) Histograms show fold change in migration activity relative to control cells (). (c) Representative images from a H2O2-induced tube formation assay after a 6-hour incubation. (d) Histograms show fold change in total cell tube length relative to control cells (). (e) Representative images of cell migration over 12 hours evaluated using a wound-healing assay in HG-induced reduction of migration. (f) Histogram shows fold change in migration activity relative to control cells (). , , and ; mean ± SD, one-way ANOVA followed by Tukey’s test.
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