Oxidative Medicine and Cellular Longevity / 2018 / Article / Tab 2

Research Article

Effects of Vitamin D3 on the NADPH Oxidase and Matrix Metalloproteinase 9 in an Animal Model of Global Cerebral Ischemia

Table 2

Activities of the GPx, GR, γGCL, and total SOD in the synaptosomal fraction of different brain structures in Group I () (sham-operated animals, which underwent the same surgical procedure without vessel occlusion (control)), group II () (subjected to ischemia/reperfusion (I/R)), and group III () (treated with vitamin D3 prior to I/R ().

Brain structureCortexHippocampus
ParameterGroup

GPx (U/mg protein)Ctrl29.34 ± 4.2038.91 ± 3.62
I/R31.40 ± 3.9127.85 ± 5.22
31.60 ± 1.7826.25 ± 4.79

GR (U/mg protein)Ctrl15.76 ± 3.16.68 ± 1.1
I/R28.58 ± 5.1128.43 ± 5.26
38.19 ± 4.1119.43 ± 4.83

γGCL (U/mg protein)Ctrl15.76 ± 0.116.68 ± 0.43
I/R28.58 ± 0.1028.43 ± 0.12
38.19 ± 0.0819.43 ± 0.29

SOD (U/mg protein)Ctrl128.61 ± 3.11129.52 ± 1.11
I/R183.36 ± 5.11192.26 ± 5.26
145.04 ± 4.05184.37 ± 4.83

Results are presented as mean ± SE. versus control and versus control.

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