Effects of Vitamin D3 on the NADPH Oxidase and Matrix Metalloproteinase 9 in an Animal Model of Global Cerebral Ischemia

Table 2

Activities of the GPx, GR, γGCL, and total SOD in the synaptosomal fraction of different brain structures in Group I () (sham-operated animals, which underwent the same surgical procedure without vessel occlusion (control)), group II () (subjected to ischemia/reperfusion (I/R)), and group III () (treated with vitamin D3 prior to I/R ().

Brain structure		Cortex	Hippocampus
Parameter	Group
GPx (U/mg protein)	Ctrl	29.34 ± 4.20	38.91 ± 3.62
	I/R	31.40 ± 3.91	27.85 ± 5.22
		31.60 ± 1.78	26.25 ± 4.79
GR (U/mg protein)	Ctrl	15.76 ± 3.1	6.68 ± 1.1
	I/R	28.58 ± 5.11	28.43 ± 5.26
		38.19 ± 4.11	19.43 ± 4.83
γGCL (U/mg protein)	Ctrl	15.76 ± 0.11	6.68 ± 0.43
	I/R	28.58 ± 0.10	28.43 ± 0.12
		38.19 ± 0.08	19.43 ± 0.29
SOD (U/mg protein)	Ctrl	128.61 ± 3.11	129.52 ± 1.11
	I/R	183.36 ± 5.11	192.26 ± 5.26
		145.04 ± 4.05	184.37 ± 4.83

Results are presented as mean ± SE. versus control and versus control.