Research Article

Dysfunction of Nrf2-ARE Signaling Pathway: Potential Pathogenesis in the Development of Neurocognitive Impairment in Patients with Moderate to Severe Obstructive Sleep Apnea-Hypopnea Syndrome

Table 3

Description of MATRICS Consensus Cognitive Battery and SCWT.

TestCognitive domainVariable of interest

TMT: part ASpeed of processingTime to complete
Symbol codingSpeed of processingTotal number correct in 90 seconds
Category Fluency Test: animal namingSpeed of processingTotal number of animals named in 60 seconds
HVLT-RVerbal learning (immediate memory)Total number of words recalled correctly over three learning trials
WMS-III: spatial spanWorking memorySum of raw scores on forward and backward conditions
NAB: mazesReasoning & problem solvingTotal raw score
BVMT-RVisual learningTotal recall score over three learning trials
CPT-IPAttention/vigilanceThe respective DPRIME values and average values for 2, 3, and 4 digits
SCWTExecutive functionThe number of words, colors, and color words in 45 seconds

TMT: Trail Making Test; HVLT-R: Hopkins Verbal Learning Test-Revised; WMS-III: Wechsler Memory Scale-Third Edition; NAB: Neuropsychological Assessment Battery; BVMT-R: Brief Visuospatial Memory Test-Revised; CPT-IP: Continuous Performance Test-Identical Pairs; SCWT: Stroop Color and Word Test.