Research Article

Dysfunction of Nrf2-ARE Signaling Pathway: Potential Pathogenesis in the Development of Neurocognitive Impairment in Patients with Moderate to Severe Obstructive Sleep Apnea-Hypopnea Syndrome

Table 5

The difference of plasma SOD and Trx levels between the control and OSAHS groups.

Control group ()OSAHS group () value

SOD (ng/ml)312.7 (248.0–387.8)78.2 (46.4–224.6)≤0.001b
Trx (ng/ml)17.93 ± 9.611.5 ± 3.320.002a

SOD, superoxide dismutase; Trx: thioredoxin. aStudent’s t-test (data are presented as mean ± SD). bMann–Whitney U test (data are presented as median (minimum-maximum)). .