Dysfunction of Nrf2-ARE Signaling Pathway: Potential Pathogenesis in the Development of Neurocognitive Impairment in Patients with Moderate to Severe Obstructive Sleep Apnea-Hypopnea Syndrome

Table 7

Correlation between sleep breathing parameters and neurocognitive function test scores in the OSAHS group.

	AHI	ODI	LSaO2	MSaO2	TSat90 (%)	REM%	ESS
NAB: mazes		−0.385	0.324	0.482	−0.498	0.099	−0.397
		0.010	0.032	0.001	0.001	0.524	0.008
SCWT-color-word		0.124	0.037	0.217	−0.314	−0.401	−0.130
		0.422	0.809	0.157	0.038	0.007	0.402
SCWT-color		0.069	0.175	0.194	−0.305	−0.142	−0.289
		0.658	0.256	0.206	0.044	0.356	0.057
CTP-IP-4D		0.011	−0.034	0.097	−0.056	−0.150	−0.307
		0.941	0.825	0.531	0.717	0.330	0.043

AHI, apnea-hypopnea index; ODI, oxygen desaturation index; LSaO₂, lowest oxygen saturation; MSaO₂, mean oxygen saturation; TSat90, % of time SaO₂ < 90%; REM%, percent of rapid eye movement in total sleep time; ESS, Epworth Sleepiness Scale; NAB: mazes, Neurological Assessment Battery: mazes; SCWT, Stroop Color and Word Test; CTP-IP, Continuous Performance Test-Identical Pairs. Data are presented as correlation coefficients (r) and p values from partial correlation analysis (adjusted covariates: age, education, sex, and smoking index). and .