Dysfunction of Nrf2-ARE Signaling Pathway: Potential Pathogenesis in the Development of Neurocognitive Impairment in Patients with Moderate to Severe Obstructive Sleep Apnea-Hypopnea Syndrome

Table 8

Correlation between plasma SOD and Trx and sleeping breathing parameters in the OSAHS group.

	AHI	ODI	LSaO2	MSaO2	REM%	TSat90 (%)
SOD		−0.331	0.133	0.299	0.078	−0.275
		0.030	0.396	0.051	0.619	0.075
Trx		−0.264	0.201	0.352	0.096	−0.385
		0.083	0.190	0.019	0.537	0.010

Data are presented as correlation coefficients (r) and values from partial correlation analysis (adjusted covariates: age, education, sex, BMI, and smoking index. and . SOD, superoxide dismutase; Trx, thioredoxin; AHI, apnea-hypopnea index; ODI, oxygen desaturation index; LSaO₂, lowest oxygen saturation; MSaO₂, mean oxygen saturation; TSat90, % of time SaO₂ < 90%; REM%, percent of rapid eye movement in total sleep time.