Review Article
Biological Effects of Tetrahydroxystilbene Glucoside: An Active Component of a Rhizome Extracted from Polygonum multiflorum
| Experimental model | IC50/dose | Effects and possible mechanism | Reference number |
| | 33.24 μΜ | Scavenge DPPH radical | [24] | | 2.75 and 0.57 μg/ml | Scavenge ⋅OH and superoxide anion radical | [8] | HBMECs | 50 and 100 μM | ↓ MDA and ROS; ↑ SOD and GSH | [25] | Rats | 20 and 40 mg/kg | ↑ SOD, GSH-Px activities; ↓ thiobarbituric acid reactive species content | [26] | Hypertensive rats | 50 mg/kg | ↓ Serum MDA and tissue 8-OHDG levels; ↑ serum GSH-Px activity | [27] | GES-1 cells and SGC-7901 cells | 5 and 10 μM | ↓ ROS production; ↑ the expression of HO-1 and NQO1 | [30] |
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