Biological Effects of Tetrahydroxystilbene Glucoside: An Active Component of a Rhizome Extracted from Polygonum multiflorum

Table 1

Antioxidative effect.

Experimental model	IC50/dose	Effects and possible mechanism	Reference number
	33.24 μΜ	Scavenge DPPH radical	[24]
	2.75 and 0.57 μg/ml	Scavenge ^⋅OH and superoxide anion radical	[8]
HBMECs	50 and 100 μM	↓ MDA and ROS; ↑ SOD and GSH	[25]
Rats	20 and 40 mg/kg	↑ SOD, GSH-Px activities; ↓ thiobarbituric acid reactive species content	[26]
Hypertensive rats	50 mg/kg	↓ Serum MDA and tissue 8-OHDG levels; ↑ serum GSH-Px activity	[27]
GES-1 cells and SGC-7901 cells	5 and 10 μM	↓ ROS production; ↑ the expression of HO-1 and NQO1	[30]