How Could We Influence Systemic Inflammation in Allergic Rhinitis? The Role of H1 Antihistamines

Table 2

Plasmatic values of total IgE and adhesion molecules in healthy volunteers and patients with AR.

Parameter	Healthy volunteers ()	Patients with AR ()
Total IgE (UI/l)	<100	115 (45.3–169)	<0.001
ICAM-1 (ng/ml)	111.21 (100–206.30)	218.19 (189.13–266.65)	0.001
VCAM-1 (ng/ml)	557 (249–891)	1004.02 (822.32–1174.68)	<0.001
E-selectin (ng/ml)	32.03 (23.68–45.94)	33.81 (24.61–47.53)	0.404

Data are expressed as median, 25–75th percentile. Significance .