How Could We Influence Systemic Inflammation in Allergic Rhinitis? The Role of H1 Antihistamines

Table 3

Patients’ biological parameters before and after treatment.

Parameter		Desloratadine ()	Levocetirizine ()
Total IgE	Baseline	116.5 (46.25–269)	115 (45.3–269)	0.212
	4 weeks	65 (28.32–167.5)	75 (30–150)
Eo	Baseline	5.00 (3.20–6.50)	5.20 (2.70–7.80)	0.04
	4 weeks	4.10 (2.60–5.80)	4 (2.35–6.35)
VCAM-1	Baseline	1037.8 (878.19–1200.82)	919.32 (818.5–1136.02)	0.202
	4 weeks	1037.98 (897.64–1193.09)	913.56 (703.58–1128.60)
ICAM-1	Baseline	208.12 (179.95–259.04)	229.81 (195.75–275.21)	0.355
	4 weeks	205.58 (170.93–256.01)	206.13 (182.74–270.14)
E-selectin	Baseline	33.54 (25.72–46.57)	33.81 (23.95–50)	0.459
	4 weeks	33.07 (24.46–44.89)	31.90 (22.08–49.5)
FeNO	Baseline	38 (19–49)	23 (16.25–43)	0.05
	4 weeks	14 (11–21)	17.5 (14–22.5)

Data are expressed as median, 25–75th percentile. Significance .