Protective Effect of Increased Zinc Supply against Oxidative Damage of Sublingual Gland in Chronic Exposure to Cadmium: Experimental Study on Rats

Table 2

The impact of zinc on TOS and TAS levels, and the TOS/TAS ratio in the sublingual gland of rats exposed to cadmium.

	TOS; (nmol/mg of protein)	TAS; (nmol/mg of protein)	TOS/TAS
Control	21.846 ± 3.751	3.466 ± 0.468	7.709 ± 1.971
30 mg Zn/dm^3	16.393 ± 1.157	7.843 ± 0.590^a‡	2.181 ± 0.236^a†
60 mg Zn/dm^3	17.951 ± 0.985	6.138 ± 0.839^a‡b	3.272 ± 0.435^a
5 mg Cd/dm^3	36.284 ± 3.438^a‡b‡c‡	1.770 ± 0.080^a^b‡c‡	20.565 ± 1.796^a‡b‡c‡
5 mg Cd/dm^3 + 30 mg Zn/dm^3	19.700 ± 1.557^d‡	7.879 ± 0.379^a‡c^d‡	2.515 ± 0.519^a†d‡
5 mg Cd/dm^3 + 60 mg Zn/dm^3	20.974 ± 1.626^d‡	12.009 ± 0.559^a‡b‡c‡d‡e‡	1.777 ± 0.157^a†d‡
50 mg Cd/dm^3	44.153 ± 3.943^a‡b‡c‡d^e‡f‡	1.930 ± 0.213^a^b‡c‡e‡f‡	24.208 ± 2.543^a‡b‡c‡d^e‡f‡
50 mg Cd/dm^3 + 30 mg Zn/dm^3	21.205 ± 2.054^d‡g‡	5.382 ± 0.627^a^b†d‡e†f‡g‡	4.093 ± 0.411^d‡g‡
50 mg Cd/dm^3 + 60 mg Zn/dm^3	26.684 ± 2.313^b^c^d†g‡	5.104 ± 0.454^a^b‡d‡e‡f‡g‡	5.433 ± 0.533^d‡g‡

The values are arithmetic means ± SEM. ; ; as compared to ^acontrol, ^b30 mg Zn/dm³, ^c60 mg Zn/dm³, ^d5 mg Cd/dm³, ^e5 mg Cd/dm³ + 30 mg Zn/dm³, ^f5 mg Cd/dm³ + 60 mg Zn/dm³, ^g50 mg Cd/dm³, and ^h50 mg Cd/dm³ + 30 mg Zn/dm³.