Hydrogen Sulfide Abrogates Hemoglobin-Lipid Interaction in Atherosclerotic Lesion

Figure 2

Double immunohistochemistry is demonstrating CSE expression in different cellular compartments of early (left) and complicated (right) atherosclerotic plaques of the carotid artery. Upper panels: CSE (DAB, brown color) and CD4 (VIP, violet) highlighting tissue macrophages (arrows); middle panels: CSE (DAB, brown color) and CD34 (VIP, violet) presenting endothelial cells (arrows); and lower panels: CSE (DAB, brown color) and smooth-muscle actin (VIP, violet) referring to smooth-muscle cells (arrows) and myofibroblasts (asterisk) (×400 magnification).