Clinical Study

Oxidative Stress in Women Treated with Atosiban for Impending Preterm Birth

Table 3

Analysis of levels of oxidative stress markers in groups with labor before and after 37 weeks of gestation before and after 48 hours of continuous administration of tocolytic therapy with Atosiban.

VariableBirth before 37 weeks ()Birth after 37 weeks () value

TOS (μmol/L)0 h24.847 ± 19.18315.839 ± 14.1350.060
48 h42.803 ± 34.68325.792 ± 27.8210.031
TAS (mmol/L)0 h0.937 ± 0.3310.934 ± 0.3950.612
48 h0.580 ± 0.3360.565 ± 0.3050.636
Carbonyl groups (μmol/L)0 h61.670 ± 28.55568.606 ± 30.3860.428
48 h96.231 ± 37.574101.104 ± 36.8720.654

Data are presented as mean value and standard deviation. TOS: total oxidant status; TAS: total antioxidant status. Analysis of variance tests were used to examine the relationship between time of labor and levels of markers of oxidative stress.