The Protective Effect of New Compound XH-103 on Radiation-Induced GI Syndrome

Figure 1

Synthesis and structure of TZ (XH-103). (a) The thiazolidine was reacted with bis(trichloromethyl) carbonate with triethylamine as base to prepare thiazolidine-3-carbonyl chloride. (b) Thiazolidine-3-carbonyl chloride was coupled with quercetin in the presence of triethylamine and 4-dimethylaminopyridine to afford the product TZ.

(a)

(b)