The Protective Effect of New Compound XH-103 on Radiation-Induced GI Syndrome

<div>XH-103 decreases the expression of p53 and Bax after TBI. The small intestinal sections of the control, IR + vehicle, and IR+ 103 mice were gained at 3 d after 9.0 Gy TBI. (a) Representative immunofluorescence images for the expression of p53 of the small intestines (red, p53; blue, DAPI). (b) Histogram showing quantitative analysis of p53-positive cells per field of view. (c) Western blot for Bax and tubulin in the intestinal crypts from non-IR mice, vehicle-treated mice, and XH-103-treated mice at 3 d after 9.0 Gy TBI. 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Oxidative Medicine and Cellular Longevity

fig7

Figure 7

Figure 7: The Protective Effect of New Compound XH-103 on Radiation-Induced GI Syndrome 