Antifibrogenic Influence of Mentha piperita L. Essential Oil against CCl₄-Induced Liver Fibrosis in Rats

Figure 2

Histopathological examination of the liver tissues (H&E, ×200). (a) Group 1 (normal control) showing normal histological picture of the liver. (b) Group 2 (fibrosis control) showing fatty degeneration of the hepatocytes, hepatocellular necrosis, and mononuclear inflammatory cells aggregation along the collagenous septa. (c) Group 3 (MPEO-treated) showing moderate hepatocellular necrosis, marked reduction of collagenous septa formation and mononuclear inflammatory cells aggregation. (d) Group 4 (MPEO control) showing normal hepatic cellular architecture.

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