Antifibrogenic Influence of Mentha piperita L. Essential Oil against CCl₄-Induced Liver Fibrosis in Rats

Table 3

Effects of MPEO on liver enzymes, NO content, and lipid peroxidation byproduct (MDA) in CCl₄-induced liver fibrosis.

Experimental groups	ALT (U/L)	AST (U/L)	MDA (μM/g tissue)	NO (mmol/L)
Group 1	18.4 ± 0.84	46 ± 1.52	60.8 ± 2.47	3.98 ± 0.32
Group 2	1147.2 ± 42.25	1088 ± 65.73	143.8 ± 3.97	16.21 ± 0.89
Group 3	882 ± 83.19	657 ± 31.74	89.14 ± 3.16	7.11 ± 0.72
Group 4	34 ± 1.12	69 ± 1.47	71.32 ± 2.36	5.42 ± 0.68

Group 1: normal control; group 2: liver fibrosis control; group 3: MPEO-treated; group 4: MPEO control. Values are expressed as mean ± SE. Different superscripts mean significant differences between groups in the same column at . ALT: alanine transaminase; AST: aspartate transaminase; NO: nitric oxide; MDA: malondialdehyde.