Research Article

Effects of Long-Term Treatment with a Blend of Highly Purified Olive Secoiridoids on Cognition and Brain ATP Levels in Aged NMRI Mice

Table 3

Basal ATP level and ATP concentrations after incubation for 24 h in SY5Y-Mock cells with POS of different concentrations (0.001 nM–10 μM) and after insult with rotenone (250 nM) in SH-SY5Y-Mock cells; basal ATP concentrations served as control, mean ± SEM, one-way ANOVA with Bonferroni posttest; , , .

Correlated valuesATP (% of control)ATP after insult (% of control)

0.001 nM vs. control102.6 ± 2.966.9 ± 1.2
0.1 nM vs. control110.6 ± 2.070.6 ± 1.5
10 nM vs. control114.9 ± 3.370.3 ± 2.56.1
1 μM vs. control111.3 ± 1.870.4 ± 2.4
10 μM vs. control103.4 ± 1.767.1 ± 1.6