Table 5: Activities of the respiratory chain complexes I and IV in isolated mitochondria of young, aged, and aged mice fed with POS determined using an Oxygraph-2k; , mean ± SEM. GPx-1 was measured in brain homogenate using a calorimetric kit;  ± SEM. CS activity was measured in isolated mitochondria;  ± SEM.

Correlated valuesCI activity [(pmol/sIU CS)]CIV activity [(pmol/sIU CS)]GPx-1 activity (mU/mL)CS activity (IU/mg protein)

Young vs. aged1545 ± 101 vs. 1625 ± 805487 ± 157 vs. 5673 ± 1911139 ± 50 vs. 1032 ± 48927 ± 108 vs. 898 ± 104
Aged vs. aged + POS1625 ± 80 vs. 1587 ± 1085673 ± 191 vs. 5806 ± 1451032 ± 48 vs. 1116 ± 60898 ± 104 vs. 843 ± 118