Research Article
Short-Duration Swimming Exercise after Myocardial Infarction Attenuates Cardiac Dysfunction and Regulates Mitochondrial Quality Control in Aged Mice
Figure 6
SIRT3 deficiency exacerbates SI-induced cardiomyocyte apoptosis and oxidative stress. (a) Effect of SIRT3 silencing on cell death, determined by LDH release assay. (b) Effect of SIRT3 silencing on apoptotic events, determined by caspase-3 activity assay. (c–e) Effect of SIRT3 silencing on mitochondrial ROS production, determined by MitoSOX Red dye. Scale bars, 10 μm. (f) Ac-SOD2 to SOD2 ratio upon SIRT3 inhibition. , versus the SI + NC group. .
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