Short-Duration Swimming Exercise after Myocardial Infarction Attenuates Cardiac Dysfunction and Regulates Mitochondrial Quality Control in Aged Mice
Table 1
Physical and echocardiographic parameters of aged mice after 8 weeks of swimming training.
Parameter
Mean ± SEM
Sham ()
MI-sedentary ()
MI + 15’ ST ()
MI + 60’ ST ()
Physical characteristic
BW (g)
30.3 ± 0.73
31.2 ± 0.71
27.7 ± 0.35
27.7 ± 0.66
Heart (mg)
140 ± 4.7
200 ± 4.7
130 ± 3.7##
180 ± 7.8,&&
HW/BW (mg/g)
4.6 ± 0.22
6.4 ± 0.26
4.7 ± 0.13#
6.6 ± 0.37,&
Tibial length (cm)
2.3 ± 0.04
2.3 ± 0.04
2.3 ± 0.04
2.3 ± 0.03
HW/TL (mg/cm)
61.0 ± 2.44
87.5 ± 3.24
57.5 ± 1.83#
80.0 ± 3.40,&
Echocardiography
LVEF (%)
67.8 ± 2.21
31.3 ± 2.24
49.5 ± 1.82,##
34.6 ± 2.14,&&
LVFS (%)
38.3 ± 0.98
17.5 ± 1.46
25.1 ± 1.59,#
19.7 ± 1.47,&
LVEDD (mm)
4.0 ± 0.13
5.2 ± 0.23
4.4 ± 0.09#
5.5 ± 0.30,&
LVESD (mm)
2.3 ± 0.18
3.9 ± 0.16
2.9 ± 0.09#
3.8 ± 0.28,&
versus the sham group; , versus the MI-sedentary group; , versus the MI + 15’ ST group. . BW, body weight; HW, heart weight; TL, tibial length; LVEF, left ventricular ejection fraction; LVFS, left ventricular fractional shortening; LVEDD, left ventricular end-diastolic diameter; LVESD, left ventricular end-systolic diameter.