Low-Frequency Intermittent Hypoxia Promotes Subcutaneous Adipogenic Differentiation

Figure 3

Intermittent hypoxia (IH) caused smaller size of adipocytes with an increase in number in subcutaneous adipose tissue (SAT) but not in visceral adipose tissue (VAT). (a–d) Photomicrographs of adipocytes from rat adipose tissue (hematoxylin-eosin staining, ×20 magnification): (a) and (c) SAT and VAT of IN group, respectively; (b) and (d) SAT and VAT of IH group, respectively, SAT but not VAT with smaller size of adipocytes and the elevation of number of adipocytes, suggesting the presence of hyperplasia.