Research Article

A Pilot Study Providing Evidence for a Relationship between a Composite Lifestyle Score and Risk of Higher Carotid Intima-Media Thickness: Is There a Link to Oxidative Stress?

Table 1

RBLS’s point assignment scheme.

Lifestyle componentCorrelation coefficient with TAC/HPX ratio

Energy storage (0.11–0.33 points)
VAT fat mass (g)1 = high (3rd tertile)2 = medium (2nd tertile)3 = low (1st tertile)−0.11
Nutritional factors (1.4–4.2 points)
PUFA intake1 = high (3rd tertile)2 = medium (2nd tertile)3 = low (1st tertile)0.14
Trans-FA intake1 = high (3rd tertile)2 = medium (2nd tertile)3 = low (1st tertile)−0.05
Iron intake1 = high (3rd tertile)2 = medium (2nd tertile)3 = low (1st tertile)0.10
Vitamin E intake1 = low (1st tertile) or higher than 270 mg2 = medium (2nd tertile)3 = high (3rd tertile)0.19
Vitamin C intake1 = low (1st tertile) or higher than 500 mg2 = medium (2nd tertile)3 = high (3rd tertile)0.09
α-Carotene intake1 = low (1st tertile) or higher than 15 mg2 = medium (2nd tertile)3 = high (3rd tertile)0.29
β-Carotene intake1 = low (1st tertile) or higher than 15 mg2 = medium (2nd tertile)3 = high (3rd tertile)0.19
Lycopene intake1 = low (1st tertile) or higher than 15 mg2 = medium (2nd tertile)3 = high (3rd tertile)0.04
Lutein and zeaxanthin intake1 = low (1st tertile) or higher than 15 mg2 = medium (2nd tertile)3 = high (3rd tertile)0.17
β-Cryptoxanthine intake1 = low (1st tertile) or higher than 15 mg2 = medium (2nd tertile)3 = high (3rd tertile)0.14
Common social drug use (0.44–1.32 points)
Caffeine intake1 = high (3rd tertile)2 = medium (2nd tertile)3 = low (1st tertile)−0.28
Alcohol intake1 = high (>1 drink/day)2 = medium (1 drink/day)3 = low (None)−0.14
Smoking history1 = current smoker2 = previous smoker3 = never smoker−0.02
Physical activity (0.38–1.14 points)
Physical activity1 = sedentary/low2 = moderate3 = high0.17
Sitting time1 = high (3rd tertile)2 = medium (2nd tertile)3 = low (1st tertile)−0.21
Psychological factors (0.34–1.02 points)
Depression score1 = high (3rd tertile)2 = medium (2nd tertile)3 = low (1st tertile)−0.18
Stress score1 = high (3rd tertile)2 = medium (2nd tertile)3 = low (1st tertile)−0.09
Anxiety score1 = high (3rd tertile)2 = medium (2nd tertile)3 = low (1st tertile)0.07
Sleep quality (0.52–1.56 points)
PSQI1 = high (3rd tertile)2 = medium (2nd tertile)3 = low (1st tertile)−0.25
Apnoea risk1 = high3 = low0.27

TAC: total antioxidant capacity; HPX: hydroperoxide; VAT: visceral adipose tissue; PUFA: polyunsaturated fatty acids; PSQI: Pittsburgh sleep quality index. Comparisons were made using Pearson’s correlation unless otherwise stated; comparisons were made using Spearman’s correlation; ; points were calculated by multiplying the point value of each lifestyle component by the (absolute) correlation coefficient of the association between the relevant component and plasma redox balance index of TAC/HPX ratio; the level previously linked to oxidative activity [34, 35].