Puerarin Mitigates Diabetic Hepatic Steatosis and Fibrosis by Inhibiting TGF-β Signaling Pathway Activation in Type 2 Diabetic Rats

Figure 6

PUR relieved oxidative stress in diabetic rats. PUR 100 mg/kg was orally administered to diabetic rats for eight weeks. (a) Representative picture of immunohistochemical staining of 3-NT, magnified by 400x, and the quantitative results of positive area assessed by ImageJ (b). Data are , per group. Serum levels of MDA (c) and 8-OHdG (d) were measured. Total antioxidant capacity of liver tissue was assayed and expressed as Trolox equivalent antioxidant capacity (e), the activity of SOD (f) of serum, and activity of CAT of liver tissue (g) were measured. Data are presented as , per group. , and compared versus DM.

(a)

(b)

(c)

(d)

(e)

(f)

(g)