Research Article
Taurine Attenuates Calpain-2 Induction and a Series of Cell Damage via Suppression of NOX-Derived ROS in ARPE-19 Cells
Figure 4
NOX4, p22phox, and NOX5 modulate loss of calcium homeostasis and ER stress in ARPE-19 cells. (a–c) Silencing of NOX2/NOX4/p22phox/NOX5 decreases its protein level. (d–g) The activities of ER stress and calpain-2 were suppressed by siRNA knockdown of NOX4, p22phox, and NOX5. The data are presented as the means ± SEM of three independent experiments. compared to the control group. and compared with the EBSS group.
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