Aerobic Training Prevents Heatstrokes in Calsequestrin-1 Knockout Mice by Reducing Oxidative Stress

Table 1

Body weight and functional output of mice before and after training.

	Pretraining; (2 months of age)		Posttraining; (4 months of age)
	WT; ()	CASQ1-null; ()	Untrained		Trained
			WT; ()	CASQ1-null; ()	CASQ1-null; ()
Body weight (g)	24.6 ± 2.9	23.6 ± 2.5	29.9 ± 2.8	27.0 ± 2.9	25.7 ± 3.0
Grip strength normalized (peak force g/g weight)	9.7 ± 1.5	3.9 ± 1.6	7.9 ± 1.7	3.0 ± 0.8^†	4.8 ± 1.1^#
Max. speed in the incremental test (m/min)	24.8 ± 3.1	27.8 ± 3.0	24.0 ± 2.1	28.1 ± 2.7^†	32.5 ± 3.9^#

Data are shown as mean ± SD. compared to age-matched WT, as evaluated by two-tailed unpaired Student’s t-test for the 95% confidence intervals; when compared to WT at 4 months, and compared to untrained CASQ1-null, as evaluated by one-way ANOVA followed by Tukey’s post hoc test. All groups were tested for normal distribution by Kolmogorov-Smirnov test and outlier detection by Grubb’s test.