Methane-Rich Saline Ameliorates Sepsis-Induced Acute Kidney Injury through Anti-Inflammation, Antioxidative, and Antiapoptosis Effects by Regulating Endoplasmic Reticulum Stress

<div>Methane-rich saline ameliorated the ER stress-related apoptosis process in septic AKI. (a) The protein levels of ER stress-related apoptosis signaling components (GRP78/ATF4/CHOP/caspase-12) were detected by Western blot, and the relative band intensities (fold of the sham group) were shown in (b). CHOP was detected by immunohistochemistry, and the quantity of CHOP-positive cells was counted in a high-power field (c). 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Oxidative Medicine and Cellular Longevity

fig6

Figure 6

Figure 6: Methane-Rich Saline Ameliorates Sepsis-Induced Acute Kidney Injury through Anti-Inflammation, Antioxidative, and Antiapoptosis Effects by Regulating Endoplasmic Reticulum Stress 

Figure 6 | Methane-Rich Saline Ameliorates Sepsis-Induced Acute Kidney Injury through Anti-Inflammation, Antioxidative, and Antiapoptosis Effects by Regulating Endoplasmic Reticulum Stress 