Research Article
Diaphragm Muscle Weakness Following Acute Sustained Hypoxic Stress in the Mouse Is Prevented by Pretreatment with N-Acetyl Cysteine
Figure 1
Mouse diaphragm muscle force-frequency relationship following 8 hours of exposure to normoxia (control), hypoxia, or hypoxia + NAC. Diaphragm-specific force (mean ± SEM) expressed as force per unit cross-sectional area of muscle (N/cm2) as a function of stimulation frequencies ranging between 10 and 160 Hz; = 6–8 per group. Data were compared statistically by two-way (gas treatment × stimulation frequency) ANOVA; and . Bonferroni’s post hoc multiple comparisons test hypoxia + NAC versus hypoxia.