Diaphragm Muscle Weakness Following Acute Sustained Hypoxic Stress in the Mouse Is Prevented by Pretreatment with N-Acetyl Cysteine

Figure 7

Mouse diaphragm phospho-JNK and phospho-p38 protein contents following 8 hours of exposure to normoxia (control), hypoxia, or hypoxia + NAC. (a) Diaphragm phospho-JNK protein content (mean ± SEM) expressed as signal/μg of total protein (corrected for background signal); per group. , , and ; unpaired t tests. (b) Diaphragm phospho-p38 protein content (mean ± SEM) expressed as signal/μg of total protein (corrected for background signal);  = 6–8 per group. and ; unpaired t tests. (c) Diaphragm phospho-ERK1/2 protein content (mean ± SEM) expressed as signal/μg of total protein (corrected for background signal);  = 5–8 per group. , , and ; unpaired t tests.

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