Growth Inhibition of a Novel Iron Chelator, DpdtC, against Hepatoma Carcinoma Cell Lines Partly Attributed to Ferritinophagy-Mediated Lysosomal ROS Generation

<div>DpdtC induced ferritinophagy. (a) Western blot analysis; (b) quantification analysis. The data were obtained from three independent Western blots based on comparison of the investigated protein with <i>β</i>-actin. (1) Control (water); (2) 1 <i>μ</i>M DpdtC; (3) 2 <i>μ</i>M DpdtC; (4) 1 <i>μ</i>M DpdtC + 3-MA (1.5 mM); (5) 2 <i>μ</i>M DpdtC + 3-MA (1.5 mM). 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Oxidative Medicine and Cellular Longevity

fig7

Figure 7

Figure 7: Growth Inhibition of a Novel Iron Chelator, DpdtC, against Hepatoma Carcinoma Cell Lines Partly Attributed to Ferritinophagy-Mediated Lysosomal ROS Generation 

Figure 7 | Growth Inhibition of a Novel Iron Chelator, DpdtC, against Hepatoma Carcinoma Cell Lines Partly Attributed to Ferritinophagy-Mediated Lysosomal ROS Generation 