Phagocytosis of <i>Candida albicans</i> Inhibits Autophagic Flux in Macrophages

<div><i>Candida albicans</i> treatment reduces the autophagosome formation in THP-1-derived macrophages. (a) THP-1-derived macrophages were treated with <i>C. albicans</i> for 8 hours. Cells were then incubated with AO. (b) THP-1-derived macrophages were pretreated with RFP-GFP-LC3 before being treated with <i>C. albicans</i> (CFW stained) for 8 hours. The untreated THP-1-derived macrophages showed weak LC3 fluorescence. Chloroquine- (CQ-) treated THP-1-derived macrophages showed that LC3 gathered into clusters. 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Oxidative Medicine and Cellular Longevity

fig2

Figure 2

Figure 2: Phagocytosis of <i>Candida albicans</i> Inhibits Autophagic Flux in Macrophages 

Oxidative Medicine and Cellular Longevity

Phagocytosis of Candida albicans Inhibits Autophagic Flux in Macrophages

Figure 2